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. 1997 Mar 24;136(6):1201–1212. doi: 10.1083/jcb.136.6.1201

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Staining patterns of lamin and DNA replication factors involved in elongation in nuclei assembled in the presence of (a and d) buffer or (b, c, e, and f) ΔNLA. (a) Control nucleus stained for PCNA. (b and c) Nucleus assembled in the presence of ΔNLA stained for (b) PCNA and (c) ΔNLA. (d) Control nucleus stained for RFC. (e and f) Nucleus assembled in the presence of ΔNLA stained for (e) RFC and (f) ΔNLA. PCNA and RFC distributions are altered from the control as a consequence of lamin disruption such that PCNA and RFC colocalize with lamin aggregates in these nuclei. Confocal microscope showing sections through the middle of the nuclei. Bar, 5 μm.

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