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. 1997 Sep 22;138(6):1229–1238. doi: 10.1083/jcb.138.6.1229

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DTT-sensitive PDI mutants have a reduced rate of CPY maturation. Pulse labeling and immunoprecipitation was carried out as described in Fig. 2 A. Mutants are identified by their active-site CXXC motifs; the left panel represents the wild-type a domain.