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. 1998 Jan 12;140(1):233–245. doi: 10.1083/jcb.140.1.233

Figure 2.

Figure 2

Light microscopic analysis of vascular wound healing and neointima formation after electric injury. All sections were stained with hematoxylin-eosin. (a) uninjured u-PAR+/+ artery, revealing the presence of smooth muscle cells in the media. (b–d) artery from a u-PAR+/+ (b) and a u-PAR−/− (c) mouse (at location 5 as defined in Fig. 1) 3 wk after injury, revealing a similar neointima in u-PAR−/− as in u-PAR+/+ arteries. For comparison, an electrically injured artery from a u-PA−/− mouse (d), revealing impaired wound healing and a much smaller neointima is displayed (reproduced from reference 9). The arrows indicate the internal elastic lamina whereas the arrowheads indicate the external elastic lamina. Bar, 50 μm.