Table I.

Proliferation (in Percent) of Medial and Neointimal Cells in u-PAR^{+ /+} and u-PAR^{− /−} Arteries After Electric Injury

		Time after injury
		Week 1		Week 2		Week 3		Week 4
Neointimal cells
u-PAR+/+		11 ± 2		8 ± 2		5 ± 2		0.5 ± 0.3
u-PAR−/−		8 ± 2		15 ± 3		4 ± 1		0.3 ± 0.3
Medial cells
u-PAR+/+		29 ± 4		15 ± 4		12 ± 3		0.8 ± 0.5
u-PAR−/−		21 ± 4		37 ± 4*		23 ± 10		0.4 ± 0.3

Proliferation of medial and neointimal cells was quantified by counting the number of 5′-bromo-2′-deoxyuridine–positive nuclei on five equally spaced sections per artery across the injured segment, and were averaged per artery. The values represent the mean ± SEM of these averages in groups containing between 8 and 14 arteries. u-PAR ^+/+, wild type; u-PAR ^−/−, u-PAR deficient.  

^*  P < 0.05 vs. wild type by analysis of variance.