Table II.
Topographic Pattern of Medial Cell Repopulation
| Time after injury | Genotype | Topographic location across injury | ||||||
|---|---|---|---|---|---|---|---|---|
| Border (position 1) | Center (position 5) | Border (position 10) | ||||||
| 1 week | u-PAR+/+ | 53 ± 7 | 8 ± 3* | 58 ± 5 | ||||
| u-PAR−/− | 99 ± 12 | 22 ± 8* | 94 ± 10 | |||||
| 3 weeks | u-PAR+/+ | 62 ± 7 | 47 ± 6 | 72 ± 5 | ||||
| u-PAR−/− | 63 ± 8 | 46 ± 11 | 55 ± 13 | |||||
The data represent the mean ± SEM of the number of cells in at least seven arteries, determined at similar relative topographic locations throughout the injured arterial segment. The topographic locations are indicated on the schematically represented arteries in Fig. 1.
*
P < 0.05 versus uninjured border (positions 1 or 10) by analysis of variance with Bonferroni correction.