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. 1997 Dec 15;139(6):1383–1396. doi: 10.1083/jcb.139.6.1383

Figure 1.

Figure 1

Structure of crosslinking probes. (note 1) “Filled-in” refers to the enzymatic synthesis of double-stranded DNA from a single-strand template using BrdU or BrdC, radionucleotide, and other deoxynucleotides. (note 2) Dark arrow indicates the region of DNA that was synthesized. (note 3) Numbers (−8, −14, −15, and −21) refer to the precise positions of BrdU/BrdC substitutions. Asterisks indicate additional specific sites substituted with BrdU or BrdC. (note 4) The box shows additional noncentromeric DNA that was added to promote oligo annealing.