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. 1997 Dec 29;139(7):1597–1610. doi: 10.1083/jcb.139.7.1597

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Interphase compartmentalization of DNA is established during late telophase/early G1 in CHF cells. Asynchronous cultures were pulse labelled with BrdU (10 μM; 30 min) and after a 3-h period (similar to the duration of G2 phase), cells were harvested at hourly intervals. Late telophase/early G1 cells were checked for the presence of labelled patterns after immunodetection of BrdU-DNA. For each time point, a minimum of 60 cells were evaluated. The graph shows that each pattern peaks according to a temporal order that is the reverse of that seen during progression through S phase (see text).