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. 1997 Dec 29;139(7):1775–1783. doi: 10.1083/jcb.139.7.1775

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Schematic diagram showing the putative membrane topology of Pro-1 glucose transporter isoforms iso-1 and iso-2. Black boxes represent putative transmembrane domains. Loops above the boxes represent extracellular domains and the loops below the boxes represent intracellular domains. The hatched line of iso-1 and the bold black line for iso-2 indicate that the only sequence differences between the two isoforms occur within the NH₂-terminal domains. Iso-1 has a 130–amino acid NH₂-terminal domain, while iso-2 has a 48–amino acid NH₂-terminal domain.