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. 1998 Mar 9;140(5):991–1002. doi: 10.1083/jcb.140.5.991

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Phenotypes of cells undergoing aberrant mitosis induced by expression of INCENP_1–405. (A–E) Transfected INCENP. (A′–E′) DNA stained with DAPI. (A′′–E′′) Microtubules. (A, A′, and A′′) Normal early prometaphase. (B, B′, and B′′) Prometaphase with many chromosomes that have failed to localize to the metaphase plate (arrow). (C, C′, and C′′) Anaphase with lagging chromosomes but a relatively normal central spindle. (D, D′, and D′′) Postmitotic cell with an unusual microtubule array that has characteristics of both anaphase and interphase. Prominent microtubule bundles are absent and the array appears to spread across the entire width of the cell. (E, E′, and E′′) Failed cytokinesis with an interphase microtubule array.