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Side chain contributions to the transfer Gibbs energy (upper bound) of RCAM RNase from water to 1 M concentrations of urea, proline, sucrose, sarcosine, and TMAO. The transfer Gibbs energy changes are segregated into two classes of side chains, the hydrophobic class (W, F, Y, L, I, P, V, M, A; unfilled bars) and the polar/charged class (T, S, Q, N, K, R, H, E, D, G; filled bars).
