Table III.
Total Cross-sectional Area and Total Fiber Number of Muscles from Wild-Type and MyHC-IId Null Mice
| Tibialis anterior | Psoas | Masseter | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| w.t. | IId−/− | w.t. | IId−/− | w.t. | IId−/− | |||||||
| Cross-sectional area (μm2 × 106) | ||||||||||||
| red | 1.181 ± 0.113 | 1.774 ± 0.187 | 1.446 ± 0.116 | 0.447 ± 0.041* | — | — | ||||||
| white | 1.125 ± 0.175 | 1.550 ± 0.098 | 1.512 ± 0.015 | 0.982 ± 0.102‡ | — | — | ||||||
| total | 2.306 ± 0.297 | 2.724 ± 0.260 | 2.958± 0.101 | 1.429 ± 0.085* | 2.815 ± 0.200 | 1.912 ± 0.201‡ | ||||||
| Number of fibers | ||||||||||||
| red | 949 ± 95 | 799 ± 115 | 1059 ± 90 | 496 ± 57‡ | — | — | ||||||
| white | 759 ± 87 | 1101 ± 90 | 1067 ± 102 | 571 ± 15‡ | — | — | ||||||
| total | 1708 ± 182 | 1900 ± 27 | 2126 ± 107 | 1067 ± 50* | 2570 ± 183 | 2285 ± 240 | ||||||
Formulas for total fiber number calculations are given in Materials and Methods. For both cross-sectional areas and total fiber numbers, average deviations from the mean are given.
*
P < 0.001 compared to wild type.
‡
P < 0.005 compared to wild type.