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Sequence comparison of the BIR motif of BRUCE (amino acids 261–333) with those from other IAP relatives. Residues identical in at least four motifs (majority) are shaded. Individual BIR repeats found in a single protein are numbered (I–III). The BIR motif of BRUCE is ∼40% identical in sequence to those of other IAP relatives, with a conserved FY (left part) and CH region (right part; see text).
