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. 1999 Feb 8;144(3):497–506. doi: 10.1083/jcb.144.3.497

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Tether force in interphase and mitotic HeLa cells. (a) Average tether force in different mitotic stages. While previous studies of membrane properties were not capable of resolving each phase, the laser optical tweezers enabled us to directly measure tether force in each cell phase and to follow the same cell through mitosis. (b) Tether force in interphase and metaphase of NIH-3T3 mouse fibroblast cells. Error bars represents SEM for 10– 25 measurements. (c) Uptake of FM1-43 labeled vesicles by interphase and metaphase cells.