Figure 3.
Antibody to VEGF inhibits FGF-2–induced endothelial cell proliferation. Growth curves of HUVE (A and B) or HAE (C and D) cells in the absence (□) or in the presence of 10 ng/ml of FGF-2 (⋄) (A and C) or 30 ng/ml of VEGF (▴) (B and D) without or with addition of either 10 μg/ml of anti-VEGF (▴) or anti–FGF-2 (○) or n.i. IgG (▪). The cells were grown and counted as described in Materials and Methods. Each point represents mean and standard deviation of triplicate samples from a representative experiment.