Table I.

Number of Capillaries Proximal to and Distal from the Limbic Region of the Cornea of Mice Receiving mAb to VEGF by i.v. Injection or by Corneal Implant in the FGF-2–Containing Pellet

		i.v. injection								Pellet
		Proximal				Distal				Proximal				Distal
		vessel				vessel				vessel				vessel
		(n)*		(%)		(n)*		(%)		(n)*		(%)		(n)*		(%)
PBS		15.7 ± 1.1		100.0		41 ± 3.1		97.2		—		—		—		—
n.i. IgG		15.7 ± 1.1		100.0		42.3 ± 1.5		100.0		15.3 ± 1.0		100.0		30.0 ± 1.3		100.0
VEGF Ab		13.8 ± 1.5		87.9‡		25.2 ± 0.9		59.6§		11.3 ± 0.9		73.8‡		15.2 ± 0.9		50.7§

^* Mean of 12 eyes per group ± SEM.  

^‡  P < 0.01.  

^§  P < 0.01. Statistical analysis performed by analysis of variance.