Table I.
Distribution of BV11 Antigen (JAM) in Tissue Sections
| Cells | Distribution | |
|---|---|---|
| Endothelial | ||
| Endocardium | ++ | |
| Arteries | ++ | |
| Arterioles | ++ | |
| Veins | ++ | |
| Venules | + | |
| Capillaries | ++ | |
| High endothelial venules | + | |
| Brain large vessels | ++ | |
| Brain capillaries | ++ | |
| Brain penetrating vessels | ++ | |
| Choroid plexus vessels | ++ | |
| Blood | ||
| Hematopoietic precursors | − | |
| Monocytes | − | |
| Granulocytes | − | |
| Erythrocytes | − | |
| Megakaryocytes | ++ | |
| Epithelial | ||
| Squamous epithelium | ++ | |
| Skin | ++ | |
| Oral cavity | ++ | |
| Esophagus | ++ | |
| Respiratory epithelium | ++ | |
| Nasal cavity | ++ | |
| Trachea | ++ | |
| Bronchus | ++ | |
| Intestinal epithelium | ++ | |
| Renal epithelium | + | |
| Hepatocytes | ± | |
| Breast glands | ++ | |
| Thyroid glands | ++ | |
| Choroid plexus epithelium | ++ | |
| Lens epithelium | − | |
| Mesenchymal | ||
| Fibroblasts | − | |
| Mesothelial cells | + |
Tissue distribution of BV11 mAb was evaluated using immunohistochemistry on cryostat sections from adult mice organs, newborn mice and 14-d fetuses. For details see Materials and Methods. 600×.