Figure 5.
Sequence comparison of Bub1 and Mad3-related proteins. (A) Sequence alignment of the NH2-terminal domains of the Bub1 and Mad3-related proteins from S. cerevisiae (Sc), mouse (m), and human (h). (B) Sequence alignment of the COOH-terminal kinase domains of the Bub1-related proteins. The 12 subdomains conserved among protein kinases (Hanks and Hunter, 1995) are underlined.