Table I.
Mutations Used in This Study That Cause the Pat Phenotype
| pat alleles | Protein encoded | Cellular phenotype | Reference | |||
|---|---|---|---|---|---|---|
| unc-52(st549) | Perlecan | No muscle cell polarization, no thick or thin filaments | (53, 75) | |||
| deb-1(st555) | Vinculin | No thin filaments | (3, 75) | |||
| myo-3(st386) | Myosin heavy chain A (mhcA) | No thick filaments | (69, 75) | |||
| egl-19(st556) pka pat-5 * | α1 subunit of muscle voltage-gated | Thick and thin filaments present | (75) | |||
| Ca2+ channel (muscle) | ||||||
| pat-10(st568) | Troponin C (TnC-1) | Thick and thin filaments present | (35, 75) |
*
Previously known as pat-5(st556), subsequently found to be an allele of egl-19.