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. 1999 Jun 14;145(6):1119–1131. doi: 10.1083/jcb.145.6.1119

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Subnuclear localization of HSA18 and 19 in optical sections through 3D-preserved nuclei. Confocal z series (1 μm) of hybridization to 4% pFa–fixed 3D human dermal fibroblasts with paints for either HSA18 (a and b) or HSA19 (c and d), prepared from randomly amplified total DNA from each chromosome and detected with FITC (green-yellow) and counterstained with PI (red). Cells were either untreated (a and c) or treated with DRB (b and d). Bars, 10 μm.