Table III.
Meiotic Progression in Oocytes from MLH1 Null Females and Controls
| Prometaphase | Meta I | Ana/MII | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Apolar | Bipolar | Other* | ||||||||||
| +/− | 41 | 4 | — | — | — | |||||||
| 4 h | (91%) | (9%) | ||||||||||
| −/− | 45 | 26 | 1 | — | — | |||||||
| (63%) | (36%) | (1%) | ||||||||||
| +/− | 7 | 8 | — | 9 | — | |||||||
| 6 h | (29%) | (33%) | (38%) | |||||||||
| −/− | 7 | 40 | 7 | — | — | |||||||
| (13%) | (74%) | (13%) | ||||||||||
| +/− | 2 | 6 | — | 56 | 1 | |||||||
| 8 h | (3%) | (9%) | (86%) | (2%) | ||||||||
| −/− | 3 | 38 | 4 | — | — | |||||||
| (7%) | (84%) | (9%) | ||||||||||
| +/− | — | — | — | 39 | 26 | |||||||
| 10 h | (60%) | (40%) | ||||||||||
| −/− | — | 27 | 3 | — | — | |||||||
| (90%) | (10%) | |||||||||||
| +/− | — | — | — | 7‡ | 32 | |||||||
| 12 h | (18%) | (82%) | ||||||||||
| −/− | 3 | 42 | 5 | |||||||||
| (6%) | (84%) | (10%) | ||||||||||
| +/− | — | — | — | — | — | |||||||
| 18 h | ||||||||||||
| −/− | — | 7 | 11 | — | 3 | |||||||
| (33%) | (52%) | (14%) | ||||||||||
*
Includes cells with collapsed spindles, spindles with grossly unequal poles, and tripolar spindles.
‡
A proportion of control oocytes arrest at MI; this is a reflection of oocyte immaturity (Eppig et al., 1994).