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. 1938 Jan 31;67(2):333–343. doi: 10.1084/jem.67.2.333

THE SPARING EFFECT OF CANINE DISTEMPER ON POLIOMYELITIS IN MACACA MULATTA

Gilbert Dalldorf 1, Margaret Douglass 1, H E Robinson 1
PMCID: PMC2133560  PMID: 19870724

Abstract

1. Rhesus monkeys inoculated with canine distemper are relatively or completely immune to experimental poliomyelitis during the first 2 weeks of the distemper. 2. Monkeys convalescent from distemper are not resistant to experimental poliomyelitis. 3. Two monkeys vaccinated with distemper virus responded to poliomyelitis in a modified manner. 4. Distemper antiserum did not influence the course of experimental poliomyelitis in rhesus monkeys. 5. Equine encephalomyelitis and vaccinia encephalitis showed no sparing effect on the course of experimental poliomyelitis. 6. The concurrence of distemper and poliomyelitis in monkeys seems to represent a new immunity mechanism in the virus field.

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Selected References

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  1. Dalldorf G., Douglass M., Robinson H. E. CANINE DISTEMPER IN THE RHESUS MONKEY (MACACA MULATTA). J Exp Med. 1938 Jan 31;67(2):323–332. doi: 10.1084/jem.67.2.323. [DOI] [PMC free article] [PubMed] [Google Scholar]
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