Figure 1.

The domain structure of the fimbrin family and the N-terminal amino acid sequence of LPL and TPL. The fimbrin family is characterized by two EF hand calcium-binding domains in the N-terminal headpiece region and two α-actinin-type actin-binding domains. The sequence of amino acids 1–21 of LPL and TPL is in brackets. The sequence used to derive the LPLtat peptide is underlined. Ser-5, which is critical for LPL phosphorylation, is in bold. Note that TPL, which has not been shown to be phosphorylated, has a Gln at position 5.