Table 1.

Sequences derived from duplicate gene pairs (“Double-copy”) have experienced an elevated nonsynonymous substitution rate and decreased selective constraint relative to single-copy sequences (“Single-copy”) since the divergence of S. cerevisiae and S. bayanus

Codon super-alignments were obtained by back-translating the protein super-alignments used to create Figure 1B. The values shown are the averages of 100 pseudo-replicates. The site-pairing procedure corrects for the Davis and Petrov effect and is described in the text.

^a% Difference is the difference between the single-copy and double-copy rates as a percentage of the single-copy rate.