Table II.
Distribution of Matrix Vesicles in Different Tissue Compartments of the Growth Plate Cartilage of Limb Bones of Collagen X Deficient and Wild-Type Mice
| Growth plate zone | Number of matrix vesicles/unit volume | |||
|---|---|---|---|---|
| +/+ (n) | −/− (n) | |||
| Resting | 0 (14) | 20.5 ±3.5* (11) | ||
| Proliferating | 0 (12) | 22.9 ± 4.1* (8) | ||
| Upper hypertrophic | 18.9 ± 1.8 (12) | 11.5 ± 1.7* (11) | ||
*
Significant difference (values at P < 0.05 by two-tailed Mann-Whitney U test) between +/+, wild-type; −/−, homozygous null mutant of 129/SvJ background; n = number of tissue fields studied; values are mean ± SEM; unit volume = area of tissue scored (3.2 μm2) X section thickness (0.1 μm) = 0.32 μm3.