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. 2003 Oct 15;112(8):1211–1222. doi: 10.1172/JCI17165

Figure 2.

Figure 2

Treatment with αGalCer induced Th1- or Th2-type Ig isotype pattern in adult NZB/W or C57BL/6 mice. C57BL/6 and NZB/W mice (8–12 weeks old) were given single or multiple injections of αGalCer or PBS/vehicle control. (a and b) Serum levels of IgE and IgG2a in C57BL/6 and NZB/W mice 9 days after having been given a single injection of αGalCer or PBS control. Bars show means of ten mice, and brackets show standard errors. (c and d) Serum levels of IgE and IgG2a in C57BL/6 and NZB/W mice 30 days after completion of injections of αGalCer or PBS control twice a week for 2 weeks. Bars show means of ten mice, and brackets show standard errors. (e) Changes of the percentage of CD1d-αGalCer tetramer-positive T cells in livers of C57BL/6 and NZB/W mice before injection and 1 day and 30 days after last injection (twice a week for 2 weeks). Tetr+, tetramer positive. There are five mice at each time point. Bars show mean percentage of five mice, and brackets show standard errors.