Figure 4.

Representative transcripts induced by wild-type p53. (A–C) Expression of the indicated transcript was determined by real-time RT-PCR using samples collected at the indicated time following virus infection (8, 16, or 24 hours). Expression of β-actin was used to normalize all RT-PCR results. Open, black, grey, hatched, and crosshatched bars represent control, Adp53^wt-, Adp53^QS1-, Adp53^QS2-, and Adp53^QS1/QS2-infected samples. Each value represents the mean fold increase in expression (± SEM) determined from a minimum of three independent experiments.