Table 2.
Average properties of orthologous human and rodent mRNAs
| Property | 5′ UTR | CDS | 3′ UTR |
|---|---|---|---|
| No alignments examined | 1,416 | 1,880 | 1,590 |
| Average length* | 115 | 1,450 | 411 |
| 75th percentile | 143 | 1,773 | 543 |
| 95th percentile | 309 | 3,390 | 1,228 |
| 99th percentile | 532 | 6,543 | 2,069 |
| Average % identity | 67 | 85 | 69 |
| Average mutation distance | K = 0.455 | Ks = 0.467 | K = 0.410 |
| Ka = 0.084 | |||
| Frequency of splice junction, % | 1.03 | ND | 0.17 |
| Frequency of repetitive element, % | 3.14 | ND | 9.20 |
In the 470 cases in which the same human mRNA sequence matched to both mouse and rat orthologs (Fig. 1), only one sequence pair was chosen, on the basis of the most complete (longest) rodent sequence available. ND = not determined.
*
Excludes poly(A) and gaps in alignment.