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MeIQx-induced dG-C8-MeIQx adduct levels in UV5 CHO cell lines. Adduct levels are plotted on the ordinate versus MeIQx treatment concentration on the abscissa. Each data point represents Mean ± S.E.M. for three experiments (the S.E.M. sometimes falls within the symbol). *dG-C8-MeIQx adducts were significantly higher (p<0.001) in CYP1A1/NAT2*4- than CYP1A1/NAT2*5B-transfected CHO cells at all concentrations tested.
