Table 3.

Lumbar spine and total femoral BMD in women according to genotype and birth weight and weight at one year

		Lumbar spine BMD			Total femoral BMD
CASRV3		11	12	22	11	12	22
Birth weight (tertile)
Low <=3175 gr		0.96	0.92	0.90	0.90	0.87	0.86
		(0.18)	(0.16)	(0.13)	(0.14)	(0.12)	(0.09)
		129	51	6	129	51	6
Middle 3175-3629 gr		0.98	0.97	1.05	0.90	0.91	0.94
		(0.17)	(0.17)	(0.29)	(0.14)	(0.13)	(0.23)
		111	34	7	111	34	7
High >3629 gr		0.95	0.95	1.19	0.89	0.91	0.94
		(0.17)	(0.16)	(0.20)	(0.12)	(0.10)	(0.14)
		82	19	6	82	18	6
P value for interaction
	unadjusted	0.009			0.046
	adjusted	0.005			0.042
Weight at one year of age (tertile)
Low <=9185 gr		0.95	0.94	0.90	0.90	0.87	0.85
		(0.15)	(0.15)	(0.18)	(0.12)	(0.13)	(0.05)
		95	48	3	95	48	3
Middle 9185-9979 gr		0.98	0.89	1.08	0.91	0.87	0.91
		(0.17)	(0.14)	(0.22)	(0.14)	(0.11)	(0.19)
		100	26	10	100	26	10
High>9979 gr		0.96	0.98	1.08	0.88	0.93	0.95
		(0.19)	(0.19)	(0.31)	(0.14)	(0.11)	(0.17)
		127	30	6	127	29	6
P value for interaction
	unadjusted	0.17			0.003
	adjusted	0.07			0.000

Values are presented as means (SD). The number of subjects is in italics.

P values for interaction are given unadjusted and adjusted (on 1df) for age at clinic, BMI, physical activity score, dietary calcium intake, smoking status, alcohol unit intake per week, current social class, years since menopause, HRT use status