Figure 4.

The gene content of centromeric HLA class I. The positions of genes, pseudogenes, and gene fragments identified by blastn and blastx–beauty analysis are indicated above and below the scale with the relative width of the bar indicating the extent of the gene. The given names of previously described genes (see ref. 5 for references) are indicated above (transcriptional orientation from left to right) and below (transcriptional orientation from right to left) the bars, with the following abbreviations: Rvs, reverse transcriptase homology; HLA CLI fgt, homology to HLA-class I genomic fragment; FGF-R fgt, fibroblast growth factor receptor gene fragment. New putative genes identified as the result of this work are indicated immediately above the scale as Pg1–9 (putative gene) with homologies as described in Table 1.