Figure 5.

Proposed relationship between GPI anchor transfer and deacylation. The anchor initially transfers in an acylated form. Inositol deacylation then occurs either(i) as a subsequent reaction physically unassociated with transamidation mediated by separate factor (deacylase) or (ii) as a concerted reaction carried out by a multiprotein transamidase deacylation complex. Hatched bar, C-terminal signal peptide; solid bar, EthN-P-containing glycan of GPI donor; striped bar, N-terminal signal peptide.