Table 4.
Detection of background blood Pb levels in blood obtained from 10 adult males.a
| Pb concentration (ppb)b |
||||
|---|---|---|---|---|
| Donor no. | Anticoagulantc | ICP-MS | Microanalyzerd | Percent error |
| 1 | HP | 38.7 ± 0.1 | 36.5 ± 0.1 | 5.5 |
| 1 | CPDA | 37.9 ± 0.5 | 40.0 ± 1.4 | 5.6 |
| 1 | EDTA | 40.6 ± 0.0 | 40.4 ± 0.1 | 5.7 |
| 1 | NaC | 36.9 ± 0.1 | 39.0 ± 1.3 | 3.8 |
| 2 | NaC | 28.3 ± 0.7 | 27.2 ± 0.2 | 0.5 |
| 3 | NaC | 17.0 ± 1.0 | 16.6 ± 0.5 | 2.6 |
| 4 | NaC | 11.1 ± 0.4 | 11.6 ± 0.5 | 4.5 |
| 5 | NaC | 6.0 ± 0.0 | 7.8 ± 0.3 | 28.9 |
| 6 | NaC | 12.6 ± 0.5 | 13.1 ± 0.2 | 4.1 |
| 7 | NaC | 11.6 ± 0.6 | 11.7 ± 0.3 | 0.9 |
| 8 | NaC | 9.5 ± 0.3 | 10.0 ± 0.3 | 5.9 |
| 9 | NaC | 124.5 ± 3.8 | 127.8 ± 1.2 | 2.7 |
| 10 | NaC | 19.9 ± 0.5 | 20.6 ± 0.1 | 3.3 |
Abbreviations: CPDA, citrate, phosphate, dextrose, and adenine; EDTA, ethylenediaminetetraacetate; HP, heparin; NaC, sodium citrate.
a
Operating conditions are described in Table 1.
b
Results are presented as mean ± SD, all measured with duplicates.
c
Blood samples were obtained from a commercial supplier of human tissues (Golden West Biologicals, Inc., CA) and were not prescreened for Pb exposure.
d
Pb concentrations were calculated from Pb signals using the slope value (0.05 μA/ppb Pb) of the calibration curve constructed with 0–20 ppb of Pb in a pure medium without adding blood (see “Pb, single” curve of Figure 4).