Figure 1.
Primary structure of light chain BIF (BJP) and amyloid protein BIF (AMY). The residues marked by dashed arrows were determined from sequencing peptides generated by trypsin (T) cleavage and from enzymatic digestion with the aspartic acid-specific (Asp-N) endoproteinase. The numbering system used is as given in ref. 12 (amino acids are indicated by the single-letter code). The junction between VL and CL domains and the segments encoded by the V, J, and C genes in BJP BIF are as designated. The arrow at position 177 indicates the Asn for Ser substitution found in both proteins.