Table 1.
Hepatocellular GSH and ascorbate levels with or without ALCAR
| Age, mo | Level, nmol per 106 cells
|
|||
|---|---|---|---|---|
| Untreated
|
ALCAR-treated
|
|||
| GSH | Ascorbate | GSH | Ascorbate | |
| 3–5 | 43.7 ± 2.4 (6) | 7.3 ± 3.0 (15) | 35.5 ± 4.7 (8) | 6.6 ± 4.9 (3) |
| 22–24 | 33.3 ± 2.8 (10)† | 3.4 ± 0.7 (11)† | 22.7 ± 2.4 (8)*† | 1.8 ± 1.2 (3)*† |
Numbers in parentheses denote n value. GSH values are expressed as mean ± SEM: ascorbate values are the mean ± SD. Values with a dagger denote statistical significance between young and old rats (P < 0.03); values with an asterisk denote statistical significance from untreated animals of similar age (P < 0.05).