Table II.
Mutation Rates
| Strain | Experiment 1 | Experiment 2 | Experiment 3 | Average (SD) | ||||
|---|---|---|---|---|---|---|---|---|
| wt/pAD4 | 2.8 | 5.0 | 3.3 | 3.7 (1.1) | ||||
| wt/pAD4-bcl-2 | 2.2 | 3.3 | 2.1 | 2.5 (0.7) | ||||
| sod1Δ/pAD4 | 6.5 | 6.3 | 6.5 | 6.4 (0.1) | ||||
| sod1Δ/pAD4-bcl-2 | 3.3 | 4.3 | 5.0 | 4.2 (0.8) | ||||
| sod1Δsod2Δ/pAD4 | 7.6 | 11.3 | 8.5 | 9.1 (1.9) | ||||
| sod1Δsod2Δ/pAD4-bcl-2 | 3.7 | 7.0 | 6.3 | 5.7 (1.7) |
Cells were grown for 72 h and then plated on plates containing canavanine. Mutation to canavanine resistance is expressed as resistant cells per 106 viable cells. Three separate experiments were performed and are reported separately. The average and standard deviation are also reported.