Table I.
Clinical history of genital herpes and time of genital lesion biopsies studied
| Subjects | P1 | P2 | P3 | P4 | P5 | P6 |
|---|---|---|---|---|---|---|
| HSV serology | 1 and 2 | 2 | 1 and 2 | 1 and 2 | 1 and 2 | 2 |
| Age/gender | 46/female | 58/male | 44/female | 54/female | 42/female | 41/female |
| No. years with HSV-2 | 28 | 25 | 18 | 16 | 22 | 20 |
| Lesion site | labia | buttock | buttock | buttock | perianal | buttock |
| Stage of genital lesion at time of biopsy |
ulcer crust healed 2 wk p.h. 4 wk p.h. 6 wk p.h. 8 wk p.h. |
pustule crust 2 wk p.h. 4 wk p.h. 6 wk p.h. 8 wk p.h. |
pustule crust 2 wk p.h. 4 wk p.h. 8 wk p.h. |
crust 2 wk p.h. 6 wk p.h. |
ulcer 2 wk p.h. 6 wk p.h. |
crust 4 wk p.h. |
| HLA type | A01, 26; B07, 08 |
A01, 02; B08, 45 |
A11, 29; B07, 41 |
A02, 23; B49, 60 |
A68; B35, 44 |
A01, 02; B08, 57 |
p.h., post-healing of the lesion (skin epithelialized).