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Reduced motor axon loss, but increased sensory loss, in SOD1G85R mice lacking neurofilaments. Ventral (A–C) and dorsal (G–I) L5 roots from wild-type, NF-L +/−, and NF-L −/− mice, respectively. Ventral (D–F) and dorsal (J–L) L5 roots from end-stage NF-L +/+, NF-L +/−, or NF-L −/− mice expressing the SOD1G85R transgene. (Scale bar, 20 μm.)
