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Absence of neurofilaments slows onset of SOD1-mediated ALS in mice
| Age, days
|
|||
|---|---|---|---|
| NF-L +/+, SOD1G85R | NF-L +/−, SOD1G85R | NF-L −/−, SOD1G85R | |
| Onset | 372 ± 10 (n = 22) | 382 ± 9 (n = 28) | 416 ± 12 (n = 14) |
| Survival | 388 ± 11 (n = 24) | 397 ± 11 (n = 33) | 433 ± 14 (n = 14) |
| Duration | 21 ± 2 (n = 23) | 22 ± 2 (n = 30) | 17 ± 3 (n = 14) |
Results are mean ± SEM.
