Table I.

The Effects of Synthetic Peptides on MCC Activity

Peptide		Sequence		Source		Net charge		Presequence		MCC block
yCOX-IV1-13		1MLSLRQSIRFFKY13		yeast		+3		+*		+
yCOX-IV1-22		1MLSLRQSIRFFKPATRTLCSSR22		yeast		+5		+*		+
yCOX-VI		1MLSRAIFRNPVINRTLLRAR20		yeast		+5		+‡		+
fCOX-IV		3RAPALRRSIATTVVRCNAET22		N. crassa		+3		+‡		+
SynB2		MLSRQQSQRQSRQQSQRQSR		synthetic		+5		−§		−
pAT-III		RNASVLKSSKNAKRYLRCNLKA		antithrombin III binding domain		+7		−*		±‖
iVDAC		109RGAKFNLHFKQ119		N. crassa		+3		−‡		−
nVDAC		1MAVPAFSDIAKSANDLLNKD20		N. crassa		−1		−‡		−
cVDAC		272THKVGTSFTFES283		N. crassa		0		−‡		−

^* Glaser, S.M., and M.G. Cumsky. 1990. J. Biol. Chem. 265:8817–8822.  

^‡ Predicted but not determined.  

^§ Allison, D.S., and G. Schatz. 1986. Proc. Natl. Acad. Sci. USA. 83:9011–9015.  

^‖ pAT-III blocked from the bath side but not micropipette side.