Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1997 Oct 20;139(2):435–447. doi: 10.1083/jcb.139.2.435

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

At metaphase CENP-E extends from the kinetochore outer plate at least 50 nm along spindle microtubules. Low magnification view of a metaphase HeLa cell with chromosomes aligned at the equator between the spindle poles (asterisks). (B) Magnified view of one metaphase chromosome showing that spindle microtubules indeed associate with a kinetochore with a trilaminar structure. Five 10-nm gold particles are located to each sister kinetochore (arrows). Five additional gold particles just to the right of the boxed area represent CENP-E associated with the kinetochore of another chromosome (more clearly seen in adjacent sections). (C) Higher magnification view shows that CENP-E is located to the corona fibers of the kinetochore. op, outer plate; ip, inner plate; cf, corona fibers. Bars: (A) 2 μm; (B) 170 nm; (C) 70 nm.