Table I.
Integrin Distribution on Transfected K562 Cells
| Integrin | Percent on microvilli | Percent on body | Gold particles counted | |||
|---|---|---|---|---|---|---|
| α4β7 | 89 ± 9 | 11 ± 9 | 1,288 | |||
| α4β1 | 81 ± 7 | 19 ± 7 | 348 | |||
| αLβ2 | 31 ± 14 | 69 ± 14 | 99 | |||
| αMβ2 | 22 ± 13 | 78 ± 13 | 236 | |||
| α4β7(αLβ2c) | 90 ± 9 | 10 ± 9 | 260 | |||
| α4β7(αMβ2tc) | 87 ± 6 | 13 ± 6 | 386 | |||
| αEβ7 | 83 ± 6 | 17 ± 6 | 149 | |||
| α6β1 | 77 ± 9 | 23 ± 9 | 401 | |||
| αvβ3 | 80 ± 10 | 20 ± 10 | 2,741 |
Transfected K562 cells expressing various integrins were analyzed by immunoelectron microscopy after staining with appropriate anti-integrin antibodies. For each integrin, all gold particles in at least three photomicrographs were counted. Percentages are presented as mean ± SD.