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. 1997 May 5;137(3):633–648. doi: 10.1083/jcb.137.3.633

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Antimycin A1 + oligomycin attenuates the Ca²⁺ plateau and inhibits loading of the TG-insensitive store. (A) 2 mM Ca²⁺ was readded to TG-treated cells in the presence (dotted trace) or absence (solid trace) of 2 μM antimycin A1. Antimycin alone inhibits the plateau and store loading, although part of the reduction in loading is due to the reduced plateau. (B) Antimycin A1 applied together with 5 μg/ml oligomycin completely inhibits store loading. (C) Average response of cells selected for a final [Ca²⁺]_i plateau >1 μM from the experiment shown in B (15/278 cells). Antimycin A1 and oligomycin together completely abolish store loading even if [Ca²⁺]_i is high.