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. 1997 Jul 14;138(1):105–117. doi: 10.1083/jcb.138.1.105

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In the three-state model of dynamic instability, k _c is the frequency of spontaneous catastrophe, k _r is the frequency of spontaneous rescue, k _EI is the frequency of transition between elongation (E) and the intermediate state (I), k _IE is the frequency of transition from I to E, k _IS is the frequency of transition from I to S, and k _SI is the frequency of transition from S to I. Note that each of these transition rate constants corresponds to changes in the structure of the microtubule ends as described in the text.