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. 1997 Nov 17;139(4):1033–1046. doi: 10.1083/jcb.139.4.1033

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Mutants lacking the COOH terminus of αN-catenin result in severe gastrulation defects. (A) GFPαNcat-injected embryos develop normally. (B) GFPαNcatCterm-expressing embryos develop normally. (C and D) Both αNcatNtermGFP- and GFPαNcatNterm-injected mRNAs induce defects beginning at stage 10, here shown by rips (arrows) occurring at the dorsal lips of the embryos. Embryos are shown with the ventral side toward the top. mRNA was injected into the animal pole of one cell of two-cell embryos.