Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1997 Nov 17;139(4):1033–1046. doi: 10.1083/jcb.139.4.1033

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Histology of gastrulating embryos expressing α-catenin– GFP fusion proteins. Stage 10–11 embryos were fixed in MEMFA and imbedded in paraplast (A and C) or plastic (B, D, E, and F) for sectioning. Arrowheads point to the blastocoel (bc). The abbreviation dl denotes the presumptive dorsal side of the embryos. (A) An uninjected normal embryo. (B) An embryo injected with GFPαNcatCterm mRNA, (C) αNcatNtermGFP, and (D) GFPαNcatNterm. Embryos expressing αNcatNtermGFP completely lack the blastocoel and are disorganized compared to normal embryos. Also noticeable is the lack of integrity of the ectodermal layers in the two mutants. Higher magnification emphasizes the disorganization of cells in an embryo expressing αNcatNtermGFP compared to a normal embryo expressing GFPαNcatCterm. mRNA was injected into the animal pole of both cells of two cell embryos. Bars: (A–D) 200 μm; (E and F) 100 μm.