Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2008 Sep 1.

Published in final edited form as: Psychoneuroendocrinology. 2007 Jul 30;32(8-10):951–958. doi: 10.1016/j.psyneuen.2007.06.014

Table 3.

Association of testosterone with depressive symptoms (CES-D ≥16) stratified by CAG RL group in black and white men.

		Black men				White men
CAG RL Group	Quartiles	Cases/total N	OR^a	(95% CI)	χ₆²^b (p value)	Cases/total N	OR^a	(95% CI)	χ₆²^b (p value)
	Total Testosterone
≤18	Q1	17/67	1.00			8/45	1.00
	Q2	5/61	0.14	(0.04–0.45)		2/48	0.24	(0.04–1.24)
	Q3	7/61	0.14	(0.05–0.43)		5/34	1.00	(0.27–3.69)
	Q4	17/62	0.31	(0.11–0.85)		2/24	0.55	(0.10–3.09)
19–21	Q1	12/46	1.00			12/69	1.00
	Q2	14/38	1.99	(0.71–5.59)		9/77	0.62	(0.24–1.62)
	Q3	12/43	1.26	(0.43–3.71)		14/77	0.98	(0.40–2.40)
	Q4	7/44	0.64	(0.19–2.11)		3/56	0.25	(0.06–0.97)
22+	Q1	2/15	1.00			4/69	1.00
	Q2	3/26	0.93	(0.13–6.84)		9/59	2.58	(0.73–9.17)
	Q3	6/28	1.58	(0.25–10.22)	16.42	10/72	2.50	(0.72–8.70)	12.61
	Q4	8/34	1.74	(0.29–10.57)	(0.01)	13/91	2.09	(0.60–7.27)	(0.05)
	Bioavailable Testosterone
≤18	Q1	16/66	1.00			3/48	1.00
	Q2	13/63	0.41	(0.16–1.05)		2/33	0.91	(0.14–6.03)
	Q3	3/54	0.10	(0.03–0.38)		12/43	3.82^c	(0.93–15.63)
	Q4	14/68	0.35	(0.14–0.90)		0/27
19–21	Q1	13/43	1.00			8/69	1.00
	Q2	9/37	0.89	(0.31–2.54)		14/85	1.52	(0.59–3.92)
	Q3	12/39	1.07	(0.39–2.90)		9/68	1.18	(0.42–3.34)
	Q4	11/52	0.70	(0.25–1.93)		7/57	1.15	(0.38–3.49)
22+	Q1	2/21	1.00			5/64	1.00
	Q2	2/19	0.80	(0.10–6.80)		8/74	1.33	(0.41–4.37)
	Q3	9/27	4.01	(0.71–22.78)	15.83	11/80	1.81	(0.58–5.64)	NA
	Q4	6/36	1.67	(0.29–9.64)	(0.01)	12/73	2.16	(0.69–6.77)	(NA)

^a

Adjusted for age, body mass index, cigarettes/d, alcohol consumption (ml/d), and total physical activity score.

^b

Test statistic and p value are for the interaction between T quartiles and CAG RL groups.

^c

Quartiles 3 and 4 combined in analysis.

CES-D, Center for Epidemiologic Studies Depression Scale, OR, odds ratio, CI, confidence interval.