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. 2007 Dec 17;179(6):1219–1230. doi: 10.1083/jcb.200705046

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Copyright © 2007, The Rockefeller University Press

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Figure 6. — The absence of MyD88 does not affect SOD1^G37R mice. SOD1^G37R mice were bred with MyD88^−/− (G37R^+/−;MyD88^−/−). Four groups of crossed mice with the following genotypes were compared: G37R^+/−;MyD88^−/− (n = 9; five females and four males), G37R^+/−;MyD88^+/+ (n = 9; four females and five males), G37R^−/−;MyD88^−/− (n = 12; five females and seven males), and G37R^−/−;MyD88^+/+ (n = 12; six females and six males). (A) The disease onset curve. (B) Kaplan-Meier survival curve. (C) Disease duration histogram. Results represent mean ± the SEM of nine mice per group. (D) Growth curve. No significant difference was observed in disease onset, survival, or disease duration between G37R^+/−;MyD88^−/− and G37R^+/−; MyD88^+/+ groups.