Figure 4.
Rh1 undergoes Gq-dependent endocytosis and downregulation in an arr2-null mutant fly. (A) Ambient light induced more ERPs in the arr2-mutant fly compared with wild type. (B) Overnight light stimulation caused Rh1 reduction in arr2 flies. All other rhabdomeral proteins had unchanged levels. (C) Mutation of Gαq, and not of arr1, inhibited the Rh1 endocytosis in arr2 flies. (D) Averaged ERP numbers per ommatidium. (E) Light exposure failed to induce Rh1 downregulation in the Gαq;arr2 double mutant. *Indicates that the sample is significantly different from others in the same group.