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. 1997 Dec 1;139(5):1231–1242. doi: 10.1083/jcb.139.5.1231

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Sequence of rat MARP and of the mouse MARP promoter. Induction of MARP in denervated skeletal muscle. (A) Deduced amino acid sequence of rat MARP. The bipartite nuclear localization sequence is underlined, and the first residues of the four ankyrin repeats are in bold. (3′ UTR) Partial sequences of rat (R) and human (H) MARP mRNA with the ATTTA degradation sequences (bold). (B) MARP mRNA contents in adult rat tissues. Northern blot of comparable amounts of total RNA from heart (H), intestine (I), diaphragm muscle (M), skin (S), lung (Lu), liver (Li), kidney (Ki), brain (B), placenta (P), and gastrocnemius muscle before (D0) and 0.7, 2, 3, and 7 d after denervation, or 3 and 8 d after Botulinum toxin-A–induced paralysis (P). Note strong induction by denervation or paralysis of skeletal muscle. (C) Nucleotide sequence of the proximal promoter of mouse MARP. Muscle E-box sequences are in bold; muscle CCAC boxes are underlined.