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. Author manuscript; available in PMC: 2007 Dec 17.
Published in final edited form as: Nat Neurosci. 2007 Feb 11;10(3):321–330. doi: 10.1038/nn1854

Figure 3.

Figure 3

Stimulation of axons within the corpus callosum evokes the release of glutamate. (a) Response of an NG2+ cell to paired stimulation of corpus callosum axons (50 ms ISI), recorded at room temperature (22–24 °C) and near physiological temperature (36 °C). Evoked responses were blocked by GYKI 53655 (100 μM). (b) Series of responses evoked with stimuli of different intensities (left, traces) and plot of the peak amplitude of the responses versus stimulus intensity (right, graph). Stimulation intensities: 5, 10, 12.5, 15, 20, 30, 50 and 70 μA. (c) Averaged responses and plot of peak amplitudes of evoked AMPAR currents recorded from an NG2+ cell in response to paired stimulation. Responses were blocked by cadmium (Cd, 30 μM, blue trace) and NBQX (10 μM, red trace). Open circles, first response amplitude; closed circles, second response amplitude. (d) Bursts of EPSCs recorded from a callosal NG2+ cell in the presence of gabazine (5 μM).